Calcium α-Ketoglutarate
Chemical Name Calcium 2-oxoglutarate
Molecular Formula C5H4O5·Ca
Molecular Weight 184.16
CAS No. 71686-01-6
Characteristics
White crystalline powder, soluble in water and slightly soluble in ethanol. It is relatively stable in neutral or alkaline environments, but may become unstable and prone to decomposition in acidic environments
Quality Standards Enterprise Standard
Application & Function
Calcium α-Ketoglutarate is a compound that combines alpha ketoglutarate (alpha KG) and calcium. Its main functions include promoting energy metabolism, supporting mitochondrial function, maintaining bone health, and may play a role in antioxidant, exercise recovery, and chronic disease management.
1. Metabolic support and energy generation: Alpha ketoglutarate is a key intermediate in the tricarboxylic acid cycle (TCA cycle), directly involved in the generation of cellular energy (ATP). Supplementing can help optimize mitochondrial function, improve cellular energy metabolism efficiency, and have certain benefits for people with fatigue recovery or high energy demand, such as athletes.
2. Bone Health Maintenance: Calcium is the main component of human bones and teeth. Calcium α-Ketoglutarate can assist in preventing or improving osteoporosis by supplementing calcium elements, especially for elderly or postmenopausal women with insufficient calcium intake. In addition, alpha ketoglutarate may indirectly promote skeletal metabolic balance by regulating osteoblast activity.
3. Antioxidant and anti-inflammatory effects: Alpha ketoglutaric acid, as an antioxidant, can scavenge free radicals and reduce oxidative stress damage to cells. Research has shown that it can activate the Nrf2 pathway (a key regulator of the antioxidant defense system), enhance the body's antioxidant capacity, and inhibit the release of pro-inflammatory factors, which has a certain auxiliary effect on chronic inflammation related diseases such as cardiovascular disease.
4. Exercise and muscle recovery: During exercise, alpha ketoglutarate may delay fatigue by reducing the accumulation of ammonia, which is a metabolic byproduct of muscle fatigue. Animal experiments have shown that supplementing with alpha ketoglutaric acid can enhance muscle endurance and recovery efficiency, but further validation of human research evidence is needed.
5. Chronic Kidney Disease (CKD): Alpha ketoglutarate may assist in improving the nutritional status of CKD patients by regulating amino acid metabolism, reducing urea production.
6. Immune regulation: Some studies suggest that it can regulate T cell function and may have potential value for the recovery of autoimmune diseases or infections.
7. Anti aging research: By activating the AMPK pathway or inhibiting mTOR signaling, it may play a role in delaying age-related metabolic decline.
Package 25kg/drum
