3,3'-Diindolylmethane (DIM)
Chemical Name 3-(1H-indol-3-ylmethyl)-1H-indole
Molecular Formula C17H14N2
Molecular Weight 246.31
CAS No. 1968-05-4
Characteristics White or off-white crystalline powder. It is a non-volatile organic compound that is insoluble in water but soluble in organic solvents such as methanol, ethyl acetate, and dichloromethane.
Quality Standards Enterprise Standard
Application & Function
The main functions of DIM include regulating estrogen metabolism, acting as an estrogen blocker, sedative and sleep aid, anticonvulsant and anesthetic effects, and detoxification.
1. Regulating estrogen metabolism: DIM can regulate estrogen metabolism and help maintain the balance of estrogen levels. This has a potential role in preventing estrogen related diseases, such as breast cancer, uterine cancer, colorectal cancer, etc. It can also regulate breast problems such as breast swelling and pain, breast nodules, and improve women's breast health.
2. As an estrogen blocker: DIM does not directly block the production of estrogen, but blocks the enzyme that converts testosterone into estrogen, while promoting the production of "good" estrogen metabolites and inhibiting the production of "bad" estrogen metabolites. This helps alleviate symptoms caused by estrogen dominance, such as acne and mood swings.
3. Sedation and Sleep Aid: DIM has a natural sedative effect that can inhibit the central nervous system of the cerebral cortex, thereby helping to improve symptoms such as insomnia and neurasthenia.
4. Anticonvulsant and Anesthesia: DIM can also inhibit the central nervous system to a certain extent, has anticonvulsant effects, and can be used to treat discomfort symptoms caused by diseases such as tetanus and eclampsia. At the same time, it can also be used as an anesthetic to help alleviate severe pain.
5. Detoxification effect: Under specific circumstances, DIM also has a certain detoxification effect. For example, when patients consume toxic food, diindolylmethane can be used for detoxification under the guidance of a doctor.
6. Antitumor therapy: DIM, as an effective anti-tumor compound, is widely used in tumor treatment research and drug development. It has the effect of inhibiting the growth and spread of tumor cells, and can interfere with the survival and proliferation of tumor cells through various mechanisms, thereby achieving anti-tumor effects. DIM and its derivatives have potential clinical application prospects in the field of tumor therapy.
7. Anti inflammatory treatment: DIM has also shown good anti-inflammatory activity and is widely used in the treatment research of inflammation related diseases. It can inhibit the release of inflammatory mediators and the occurrence of inflammatory reactions, alleviate inflammatory damage and symptoms. Therefore, diindolylmethane and its derivatives have potential application prospects in the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
8. Antibacterial activity: DIM also has certain antibacterial activity, which can inhibit the growth and reproduction of various bacteria. This makes it potentially useful in the development of antibacterial drugs. DIM and its derivatives have shown certain antibacterial spectra and effects in the development of antibacterial agents, providing new ideas and directions for the development of new antibacterial drugs.
9. Prevention of symptoms of prostate hyperplasia: DIM can help reduce prostatitis, and it is often used to help control prostate enlargement. Laboratory studies have shown that DIM can help prevent and alleviate prostatitis.
Package 25kg/drum
